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Basic And Clinical Pharmacology | Download Book Pdf
The fourteenth edition of Basic & Clinical Pharmacology continues the extensive use of full-color illustrations and expanded coverage of transporters, pharmacogenomics, and new drugs of all types
emphasized in prior editions. In addition, it reflects the major expansion of large-molecule drugs in the pharmacopeia, with numerous new monoclonal antibodies and other biologic agents. Case studies accompany most chapters, and answers to questions posed in the case studies appear at the end of each chapter.
The book is designed to provide a comprehensive, authoritative, and readable pharmacology textbook for students in the health sciences. Frequent revision is necessary to keep pace with the rapid changes in pharmacology and therapeutics; the 2–3 year revision cycle of this text is among the shortest in the field, and the availability
of an online version provides even greater currency. The book also offers special features that make it a useful reference for house officers and practicing clinicians.
This edition continues the sequence used in many pharmacology courses and in integrated curricula: basic principles of drug discovery, pharmacodynamics, pharmacokinetics, and pharmacogenomics; autonomic drugs; cardiovascular-renal drugs; drugs with important actions on smooth muscle; central nervous system drugs; drugs used to treat inflammation, gout, and diseases of the blood; endocrine drugs; chemotherapeutic drugs; toxicology; and special topics. This sequence builds new information on a foundation of information already assimilated. For example, early presentation of autonomic nervous system pharmacology allows students to integrate the physiology and neuroscience they have learned elsewhere with the pharmacology they are learning and prepares them to understand the autonomic effects of other drugs.
This is especially important for the cardiovascular and central nervous system drug groups. However, chapters can be used equally well in courses and curricula that present these topics in a different sequence.
Within each chapter, emphasis is placed on discussion of drug groups and prototypes rather than offering repetitive detail about individual drugs. Selection of the subject matter and the order of its presentation are based on the accumulated experience of teaching this material to thousands of medical, pharmacy, dental,
podiatry, nursing, and other health science students. Major features that make this book particularly useful in
integrated curricula include sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects—in other words, clinical pharmacology is an integral
part of this text. Lists of the trade and generic names of commercial preparations available are provided at the end of each chapter for easy reference by the house officer or practitioner evaluating a patient’s drug list or writing a prescription.
Significant revisions in this edition include:
1. Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, antiinflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters.
2. Continued expansion of the coverage of general concepts relating to newly discovered receptors, receptor mechanisms, and drug transporters.
3. Descriptions of important new drugs released through May 2017.
4. Many revised illustrations in full color that provide significantly more information about drug mechanisms and effects and help to clarify important concepts.
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